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Showing 1 to 12 of 363 entries
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New imaging techniques in the diagnosis of multiple sclerosis.

Expert opinion on medical diagnostics

Fu Y, Talavage TM, Cheng JX.
PMID: 19337386
Expert Opin Med Diagn. 2008 Sep;2(9):1055-65. doi: 10.1517/17530050802361161.

BACKGROUND: Multiple sclerosis (MS) is a chronic disabling disorder histopathologically characterized by inflammation, demyelination and axonal loss. Conventional MRI has made most contributions to the diagnosis of MS. However, it is not sufficiently sensitive and specific to reveal the...

Emerging urinary biomarkers in the diagnosis of acute kidney injury.

Expert opinion on medical diagnostics

Devarajan P.
PMID: 19079800
Expert Opin Med Diagn. 2008 Apr;2(4):387-398. doi: 10.1517/17530059.2.4.387.

BACKGROUND: Acute kidney injury (AKI) represents a common and devastating problem in clinical medicine. The lack of early biomarkers for AKI has led to a delay in initiating potentially effective therapies. OBJECTIVE: Identification of novel urinary biomarkers for AKI...

The evolving role of nuclear molecular imaging in cancer.

Expert opinion on medical diagnostics

Kurdziel K, Ravizzini G, Croft B, Tatum J, Choyke P, Kobayashi H.
PMID: 19122861
Expert Opin Med Diagn. 2008 Jul;2(7):829-842. doi: 10.1517/17530059.2.7.829.

BACKGROUND: Novel therapies targeted to specific tumor pathways are entering the clinic. The need for in vivo monitoring of resulting molecular changes, particularly with respect to the tumor microenvironment, is growing. Molecular imaging is evolving to include a variety...

New visual information processing abnormality biomarker for the diagnosis of Schizophrenia.

Expert opinion on medical diagnostics

Koychev I, El-Deredy W, Deakin JF.
PMID: 22003364
Expert Opin Med Diagn. 2011 Jul 01;5(4):357-368. doi: 10.1517/17530059.2011.586029.

INTRODUCTION: Schizophrenia is currently diagnosed on the basis of patient reports and clinical observations. A diagnosis based on aetiology is inherently more reliable due to being closer to the disease process than the overt clinical manifestations. Accordingly, recent research...

BRAF mutation in cytology samples as a diagnostic tool for papillary thyroid carcinoma.

Expert opinion on medical diagnostics

Marotta V, Sapio MR, Guerra A, Vitale M.
PMID: 23484549
Expert Opin Med Diagn. 2011 Jul;5(4):277-90. doi: 10.1517/17530059.2011.575058. Epub 2011 Apr 21.

INTRODUCTION: Thyroid cancer is a rare disease that needs to be differentiated from the more frequent benign nodular goiter. The current, primary technique for distinguishing between benign and malignant nodules is by a fine-needle biopsy (FNB) cytological examination. This...

Antibody profiling with protein antigen microarrays in early stage cancer.

Expert opinion on medical diagnostics

Liu BC, Dijohnson DA, O'Rourke DJ.
PMID: 23480685
Expert Opin Med Diagn. 2012 May;6(3):187-96. doi: 10.1517/17530059.2012.672969. Epub 2012 Mar 22.

INTRODUCTION: Proteins not present in normal cells, that is, cancer cells, may elicit a host immune response that leads to the generation of antibodies that might react with these tumor-associated proteins. In recent years, a growing number of reports...

Functional neuroimaging in Parkinson's disease.

Expert opinion on medical diagnostics

de la Fuente-Fernández R, Appel-Cresswell S, Doudet DJ, Sossi V.
PMID: 23480585
Expert Opin Med Diagn. 2011 Mar;5(2):109-20. doi: 10.1517/17530059.2011.554820. Epub 2011 Feb 01.

INTRODUCTION: Functional neuroimaging techniques have greatly contributed to improving our understanding of Parkinson's disease (PD) neurodegeneration and related compensatory mechanisms.AREAS COVERED: In this paper, the authors analyze the role of functional neuroimaging as a diagnostic tool in PD and...

The times they are a-changin': prognostic markers in the new era of BCR-targeting therapies for CLL.

Expert opinion on medical diagnostics

Burger JA.
PMID: 23480620
Expert Opin Med Diagn. 2012 Jan;6(1):49-57. doi: 10.1517/17530059.2012.637108. Epub 2011 Nov 28.

INTRODUCTION: Given the highly variable clinical presentation and prognosis in patients with chronic lymphocytic leukemia (CLL), prognostic markers have typically been used for estimating the risk of disease progression and prognosis in individual patients. The traditional clinical staging systems...

Diagnosis of neuropathic pain: challenges and possibilities.

Expert opinion on medical diagnostics

Lauria G, Faber CG, Merkies IS, Waxman SG.
PMID: 23480652
Expert Opin Med Diagn. 2012 Mar;6(2):89-93. doi: 10.1517/17530059.2012.661712. Epub 2012 Feb 23.

Neuropathic pain complicates many diseases of the peripheral and central nervous system and is frequently encountered in clinical practice. The mechanisms underlying its occurrence and chronification remain poorly understood. As a consequence, symptomatic treatment is frequently the only available...

CTA in the evaluation of acute chest pain syndromes. Should more widespread use be advocated?.

Expert opinion on medical diagnostics

Kalia N, Budoff M.
PMID: 23480739
Expert Opin Med Diagn. 2012 Jul;6(4):275-80. doi: 10.1517/17530059.2012.676041. Epub 2012 Apr 05.

INTRODUCTION: With the advent of CT more than 3 decades ago, we have seen rapid evolution of this technology, so that we are now able to noninvasively accurately image the coronary arterial tree. This has opened up a debate...

Imaging in the diagnosis and prognosis of traumatic brain injury.

Expert opinion on medical diagnostics

Carter E, Coles JP.
PMID: 23480836
Expert Opin Med Diagn. 2012 Nov;6(6):541-54. doi: 10.1517/17530059.2012.707188. Epub 2012 Jul 19.

INTRODUCTION: Traumatic brain injury (TBI) is a major cause of death and disability worldwide. Improved understanding of the impact of head injury and the extent and development of neuronal loss and cognitive dysfunction could lead to improved therapy and...

New prognostic markers in neuroblastoma.

Expert opinion on medical diagnostics

Navarro S, Piqueras M, Villamón E, Yáñez Y, Balaguer J, Cañete A, Noguera R.
PMID: 23480837
Expert Opin Med Diagn. 2012 Nov;6(6):555-67. doi: 10.1517/17530059.2012.704018. Epub 2012 Jul 11.

INTRODUCTION: The hallmark of neuroblastoma is its clinical and biological heterogeneity, with the likelihood of cure varying widely according to age at diagnosis, extent of disease and tumor biology. We hope this review will be useful for understanding part...

Showing 1 to 12 of 363 entries